The cellular response to the environment involves complex regulatory networks that respond to stimuli such as light, pH, availability of carbon and nitrogen sources, reactive oxygen species, thermal stress, and interspecies-crosstalk ;.
Type III PKSs have originally been discovered in plants but are also present in bacteria and fungi.
However, in some breeds the smell is not very strong.
However, the discovery did not attract much attention until the 1940s when and developed methods for mass production and application in humans, incited by the urgent war-time need for antibacterial agents.
However, these transcription factors also display negative regulation.
Since the discovery of penicillin by Alexander Fleming, this filamentous fungus is used as a commercial β-lactam antibiotic producer.