Journal of General Virology, vol.
Therefore, the broad susceptibility of Vero cells has promoted the development of vaccine production using Vero cells as a substrate.
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Vero cells cannot express antiviral protein interferon due to their inherent genetic defects.
It will be apparent to those skilled in the art that various modifications and variations can be made in the cell substrate of the present invention and in its uses without departing from the spirit or scope of the invention.
Many well characterized rotaviruses have been isolated, serially passaged and triply plaque-purified is commercially available laboratory cell culture systems not suitable for vaccine production.